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Mescaline acts from the central nervous method by stimulating the serotoninergic and dopaminergic receptor [101]; the mechanism that underlines cognitive, perceptive and affective effects is not really however nicely know; on the other hand mescaline looks to have the ability to improved glutamate launch at the extent with the cerebral cortex by acting for a partial agonist of the five-HT2A receptors for serotonine [two]. At the dose of 350 mg, the 1st outcomes of mescaline are noticed at about half-hour once the ingestion, and might include things like nausea, vomiting, diarrhea, palpitations, tachycardia, elevated blood pressure level, mydriasis, obscured eyesight, respiratory problems.
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